Avignonesi Occhio di Pernice Vin Santo di Montepulciano is a type of Vin Santo produced by the Avignonesi winery located in the Montepulciano region of Tuscany, Italy. Vin Santo is a traditional Italian dessert wine made from dried grapes, typically Trebbiano and Malvasia varieties.

"Occhio di Pernice" translates to "eye of the partridge," which is a term used to describe a specific style of Vin Santo made from red grapes, in contrast to the more common white grape varieties. This wine is known for its amber color, rich flavors of dried fruits, nuts, honey, and caramel, as well as its luscious sweetness. It's often enjoyed as a dessert wine or paired with various desserts such as cantucci (biscotti).